The tRNAscan-SE Genomic tRNA Database was created and is maintained
by Todd
Lowe and Patricia Chan.
A paper describing this database is planned for submission in
2008.
(Chan and Lowe, "GtRNAdb: A database of genomic transfer RNA detection", 2008).
In the meantime, if you use the tRNA predictions given in this database, please cite:
Lowe, T.M. & Eddy, S.R. (1997) "tRNAscan-SE: A program for
improved detection of transfer RNA genes in genomic sequence"
Nucl. Acids Res. 25: 955-964.
If you find this resource helpful and use it in your research, please help support its
funding by writing a quick email to Todd (lowe@soe.ucsc.edu) describing how it has been useful
to you. Letters like these help bolster the case for future funding. (many thanks! -Todd)
tRNAscan-SE employs:
- a modified, optimized version of tRNAscan v1.3
(Fichant & Burks, J. Mol. Biol. 220: 659-671, 1991),
- a new implementation of a multistep weight matrix algorithm
for identification of eukaryotic tRNA promoter regions
(Pavesi et al., Nucl. Acids Res. 22: 1247-1256, 1994),
- the RNA covariance analysis package Cove v.2.4.2
(Eddy & Durbin, Nucl. Acids Res. 22: 2079-2088, 1994)
